Tomuţă, Ioan: search on Z-Library

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1

A step forward towards the development of stable freeze-dried liposomes. A Quality by Design approach (QbD)

Sylvester, Bianca, Porfire, Alina, Achim, Marcela, Rus, Lucia, Tomuţă, Ioan

Journal:

Drug Development and Industrial Pharmacy

Year:

2017

Language:

english

File:

PDF, 1.47 MB

english, 2017

2

QbD for Pediatric Oral Lyophilisates Development: Risk assessment followed by Screening and Optimization

Casian, Tibor, Iurian, Sonia, Bogdan, Catalina, Rus, Lucia, Moldovan, Mirela, Tomuta, Ioan

Journal:

Drug Development and Industrial Pharmacy

Year:

2017

Language:

english

File:

PDF, 1.36 MB

english, 2017

3

A quality by design (QbD) study on enoxaparin sodium loaded polymeric microspheres for colon-specific delivery

Hales, Dana, Vlase, Laurian, Porav, Sebastian Alin, Bodoki, Andreea, Barbu-Tudoran, Lucian, Achim, Marcela, Tomuță, Ioan

Journal:

European Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 1.56 MB

english, 2017

4

A quality by design approach for the development of lyophilized liposomes with simvastatin

Porfire, Alina, Muntean, Dana Maria, Rus, Lucia, Sylvester, Bianca, Tomuţă, Ioan

Journal:

Saudi Pharmaceutical Journal

Year:

2017

Language:

english

File:

PDF, 1.07 MB

english, 2017

5

A Quality by Design (QbD) Approach to the Development of a Gradient High-Performance Liquid Chromatography for the Simultaneous Assay of Curcuminoids and Doxorubicin from Long-Circulating Liposomes

Sylvester, Bianca, Tefas, Lucia, Vlase, Laurian, Tomuţă, Ioan, Porfire, Alina

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2018

Language:

english

File:

PDF, 1.07 MB

english, 2018

6

Fluidized bed granulation of two APIs: QbD approach and development of a NIR in-line monitoring method

Gavan, Alexandru, Iurian, Sonia, Casian, Tibor, Porfire, Alina, Porav, Sebastian, Voina, Ioana, Oprea, Alexandru, Tomuta, Ioan

Journal:

Asian Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 1.27 MB

english, 2019

7

Optimizing long-circulating liposomes for delivery of simvastatin to C26 colon carcinoma cells

Porfire, Alina, Tomuta, Ioan, Muntean, Dana, Luca, Lavinia, Licarete, Emilia, Alupei, Marius Costel, Achim, Marcela, Vlase, Laurian, Banciu, Manuela

Journal:

Journal of Liposome Research

Year:

2014

Language:

english

File:

PDF, 349 KB

english, 2014

8

Formulation and evaluation of a water-in-oil cream containing herbal active ingredients and ferulic acid

Moldovan, Mirela, Lahmar, Abir, Bogdan, Cătălina, Părăuan, Simona, Tomuță, Ioan, Crișan, Maria

Journal:

Year:

2017

Language:

english

File:

PDF, 533 KB

english, 2017

9

Improvement of skin condition in striae distensae: development, characterization and clinical efficacy of a cosmetic product containing Punica granatum seed oil and Croton lechleri resin extract

Bogdan, Catalina, Iurian, Sonia, Tomuta, Ioan, Moldovan, Mirela Liliana

Journal:

Drug Design Development and Therapy

Year:

2017

Language:

english

File:

PDF, 1.78 MB

english, 2017

10

The applicability of pharmaceutical polymeric blends for the fused deposition modelling (FDM) 3D technique: Material considerations–printability–process modulation, with consecutive effects on in vitro release, stability and degradation

Ilyés, Kinga, Kovács, Norbert Krisztián, Balogh, Attila, Borbás, Enikő, Farkas, Balázs, Casian, Tibor, Marosi, György, Tomuță, Ioan, Nagy, Zsombor Kristóf

Journal:

European Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 9.95 MB

english, 2019

11

Data fusion strategies for performance improvement of a Process Analytical Technology platform consisting of four instruments: An electrospinning case study

Casian, Tibor, Farkas, Attila, Ilyés, Kinga, Démuth, Balázs, Borbás, Enikő, Madarász, Lajos, Rapi, Zsolt, Farkas, Balázs, Balogh, Attila, Domokos, András, Marosi, György, Tomută, Ioan, Nagy, Zsombor K

Journal:

International Journal of Pharmaceutics

Year:

2019

Language:

english

File:

PDF, 2.91 MB

english, 2019

12

Simultaneous quantification of simvastatin and excipients in liposomes using near infrared spectroscopy and chemometry

Porfire, Alina, Muntean, Dana, Achim, Marcela, Vlase, Laurian, Tomuta, Ioan

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2015

Language:

english

File:

PDF, 1.71 MB

english, 2015

13

Development of oral lyophilisates containing meloxicam nanocrystals using QbD approach

Iurian, Sonia, Bogdan, Cătălina, Tomuță, Ioan, Szabó-Révész, Piroska, Chvatal, Anita, Leucuța, Sorin E., Moldovan, Mirela, Ambrus, Rita

Journal:

European Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 1.26 MB

english, 2017

14

In Vivo Double Targeting of C26 Colon Carcinoma Cells and Microenvironmental Protumor Processes Using Liposomal Simvastatin

Luput, Lavinia, Licarete, Emilia, Drotar, Denise Minerva, Nagy, Andras-Laszlo, Sesarman, Alina, Patras, Laura, Rauca, Valentin Florian, Porfire, Alina, Muntean, Dana, Achim, Marcela, Tomuta, Ioan, Vla

Journal:

Journal of Cancer

Year:

2018

Language:

english

File:

PDF, 1.21 MB

english, 2018

15

Piecewise function parameters as responses of the design of experiment in the development of a pulsatile release chronopharmaceutical system

Vonica-Gligor, Andreea Loredana, Tomuţă, Ioan, Leucuţa, Sorin E.

Journal:

Acta Pharmaceutica

Year:

2016

Language:

english

File:

PDF, 1.51 MB

english, 2016

16

Optimization of metoprolol tartrate modified-release matrix tablet formulation using Eudragit NE as binder for metoprolol fluid bed granulation

Tomuta, Ioan, Leucuta, SorinE, Alecu, Cristian, Dudas, Dana

Journal:

Asian Journal of Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 1.79 MB

english, 2012

17

Near Infra-Red spectroscopy for content uniformity of powder blends– focus on calibration set development, orthogonality transfer and robustness testing

Casian, Tibor, Iurian, Sonia, Gavan, Alexandru, Revnic, Cornelia, Porav, Sebastian, Porfire, Alina, Vlase, Laurian, Tomuță, Ioan

Journal:

Year:

2018

Language:

english

File:

PDF, 1.94 MB

english, 2018

18

Development, validation and comparison of near infrared and Raman spectroscopic methods for fast characterization of tablets with amlodipine and valsartan

Casian, Tibor, Reznek, Andra, Vonica-Gligor, Andreea Loredana, Van Renterghem, Jeroen, De Beer, Thomas, Tomuță, Ioan

Journal:

Year:

2017

Language:

english

File:

PDF, 1.12 MB

english, 2017

19

Investigation of a Potential Pharmacokinetic Interaction Between Nebivolol and Fluvoxamine in Healthy Volunteers

Gheldiu, Ana-Maria, Vlase, Laurian, Popa, Adina, Briciu, Corina, Muntean, Dana, Bocsan, Corina, Buzoianu, Anca, Achim, Marcela, Tomuta, Ioan, Todor, Ioana, Neag, Maria

Journal:

Journal of Pharmacy and Pharmaceutical Sciences

Year:

2017

File:

PDF, 316 KB

2017

20

Defining the Design Space for Freeze-Dried Orodispersible Tablets with Meloxicam

Iurian, Sonia, Tomuta, Ioan, Bogdan, Cătălina, Rus, Lucia, Tokes, Timea, Barbu-Tudoran, Lucian, Achim, Marcela, Moldovan, Mirela, Leucuta, Sorin

Journal:

Drug Development and Industrial Pharmacy

Year:

2016

Language:

english

File:

PDF, 1.18 MB

english, 2016

21

Original research paper. Formulation and pharmaceutical development of quetiapine fumarate sustained release matrix tablets using a QbD approach

Gavan, Alexandru, Porfire, Alina, Marina, Cristina, Tomuta, Ioan

Journal:

Acta Pharmaceutica

Year:

2017

Language:

english

File:

PDF, 1018 KB

english, 2017

22

Liposomal simvastatin sensitizes C26 murine colon carcinoma to the antitumor effects of liposomal 5âfluorouracil in vivo

Luput, Lavinia, Sesarman, Alina, Porfire, Alina, Achim, Marcela, Muntean, Dana, Casian, Tibor, Patras, Laura, Rauca, Valentin Florian, Drotar, Denise Minerva, Stejerean, Ioana, Tomuta, Ioan, Vlase, La

Journal:

Year:

2020

File:

PDF, 1.51 MB

2020

23

Development and validation of NIR-chemometric methods for chemical and pharmaceutical characterization of meloxicam tablets

Tomuta, Ioan, Iovanov, Rares, Bodoki, Ede, Vonica, Loredana

Journal:

Drug Development and Industrial Pharmacy

Year:

2014

Language:

english

File:

PDF, 518 KB

english, 2014

24

AIP Conference Proceedings [AIP PROCESSES IN ISOTOPES AND MOLECULES (PIM 2011) - Cluj Napoca, Romania (29 September–1 October 2011)] - Solid form of indapamide recrystallized from acetonitrile/diethyl ether solvent mixture

Rus, Lucia M., Kacso, Irina, Borodi, Gheorghe, Aluas, Mihaela, Tomuta, Ioan, Iuga, Cristina, Simon, Simion, Bratu, Ioan, Bojita, Marius, Lazar, Mihaela D.

Year:

2012

Language:

english

File:

PDF, 2.20 MB

english, 2012

25

Data fusion strategies for performance improvement of a Process Analytical Technology platform consisting of four instruments: An electrospinning case study

Casian, Tibor, Farkas, Attila, Ilyés, Kinga, Démuth, Balázs, Borbás, Enikő, Madarász, Lajos, Rapi, Zsolt, Farkas, Balázs, Balogh, Attila, Domokos, András, Marosi, György, Tomută, Ioan, Nagy, Zsombor K

Journal:

International Journal of Pharmaceutics

Year:

2019

File:

PDF, 2.91 MB

2019

26

Assessment of a Potential Pharmacokinetic Interaction between Nebivolol and Bupropion in Healthy Volunteers

Gheldiu, Ana-Maria, Popa, Adina, Neag, Maria, Muntean, Dana, Bocsan, Corina, Buzoianu, Anca, Vlase, Laurian, Tomuta, Ioan, Briciu, Corina

Journal:

Year:

2016

Language:

english

File:

PDF, 227 KB

english, 2016

27

High-throughput NIR-chemometric methods for chemical and pharmaceutical characterization of sustained release tablets

Porfire, Alina, Filip, Cristina, Tomuta, Ioan

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2017

Language:

english

File:

PDF, 316 KB

english, 2017

28

The pharmaceutical applications of a biopolymer isolated from Trigonella foenum-graecum seeds: Focus on the freeze-dried matrix forming capacity

Iurian, Sonia, Dinte, Elena, Iuga, Cristina, Bogdan, Cătălina, Spiridon, Iuliana, Barbu-Tudoran, Lucian, Bodoki, Andreea, Tomuţă, Ioan, Leucuţa, Sorin E.

Journal:

Saudi Pharmaceutical Journal

Year:

2017

Language:

english

File:

PDF, 1.17 MB

english, 2017

29

Quantification of ascorbic acid and sodium ascorbate in powder blends for tableting and in vitamin C chewable tablets by NIR-chemometry

Tomuţă, Ioan, Dudaş, Dana, Vonica, Andreea Loredana, Leucuţa, Sorin E.

Journal:

Acta Pharmaceutica

Year:

2013

Language:

english

File:

PDF, 520 KB

english, 2013

30

Simultaneous quantification of l-α-phosphatidylcoline and cholesterol in liposomes using near infrared spectrometry and chemometry

Alina Porfire, Ioan Tomuta, Lucia Tefas, Sorin E. Leucuta, Marcela Achim

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2012

Language:

english

File:

PDF, 552 KB

english, 2012

31

Definition and validation of the Design Space for co-milled nasal powder containing nanosized lamotrigine

Gieszinger, Peter, Casian, Tibor, Tomuta, Ioan, Bartos, Csilla, Szabó-Révész, Piroska, Ambrus, Rita

Journal:

Drug Development and Industrial Pharmacy

Year:

2018

Language:

english

File:

PDF, 1.11 MB

english, 2018

32

Risk assessment and experimental design in the development of a prolonged release drug delivery system with paliperidone

Iurian, Sonia, Turdean, Luana, Tomuta, Ioan

Journal:

Drug Design Development and Therapy

Year:

2017

Language:

english

File:

PDF, 1.89 MB

english, 2017

33

Formulation, preparation and in vitro - in vivo evaluation of compression-coated tablets for the colonic-specific release of ketoprofen

Hales, Dana, Dumitrașcu, Dan Lucian, Tomuță, Ioan, Briciu, Corina, Muntean, Dana-Maria, Tefas, Lucia Ruxandra, Iurian, Sonia, Iovanov, Rareș Iuliu, Achim, Marcela, Vlase, Laurian

Journal:

Brazilian Journal of Pharmaceutical Sciences

Year:

2018

Language:

english

File:

PDF, 1.68 MB

english, 2018

34

High-throughput NIR-chemometric methods for determination of drug content and pharmaceutical properties of indapamide powder blends for tabletting

Alina Porfire, Lucia Rus, Andreea Loredana Vonica, Ioan Tomuta

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2012

Language:

english

File:

PDF, 555 KB

english, 2012

35

OPTIMIZATION OF PREDNISOLONE-LOADED LONG-CIRCULATING LIPOSOMES via APPLICATION OF QUALITY BY DESIGN (QbD) APPROACH

Sylvester, Bianca, Porfire, Alina, Muntean, Dana-Maria, Vlase, Laurian, Luput, Lavinia, Licarete, Emilia, Sesarman, Alina, Alupei, Marius Costel, Banciu, Manuela, Achim, Marcela, Tomuţă, Ioan

Journal:

Journal of Liposome Research

Year:

2016

Language:

english

File:

PDF, 1.05 MB

english, 2016

36

Influence of Mixed Additives on the Physicochemical Properties of a 5.25% Sodium Hypochlorite Solution: An Unsupervised Multivariate Statistical Approach

Dragan, Oana, Tomuta, Ioan, Casoni, Dorina, Sarbu, Costel, Campian, Radu, Frentiu, Tiberiu

Journal:

Journal of Endodontics

Year:

2017

Language:

english

File:

PDF, 1.06 MB

english, 2017

37

Development of a NIR Method for the In-Line Quantification of the Total Polyphenolic Content: A Study Applied on Ajuga genevensis L. Dry Extract Obtained in a Fluid Bed Process

Gavan, Alexandru, Colobatiu, Liora, Mocan, Andrei, Toiu, Anca, Tomuta, Ioan

Journal:

Year:

2018

Language:

english

File:

PDF, 2.34 MB

english, 2018

38

Process Optimization for Improved Phenolic Compounds Recovery from Walnut (Juglans regia L.) Septum: Phytochemical Profile and Biological Activities

Rusu, Marius, Gheldiu, Ana-Maria, Mocan, Andrei, Moldovan, Cadmiel, Popa, Daniela-Saveta, Tomuta, Ioan, Vlase, Laurian

Journal:

Year:

2018

Language:

english

File:

PDF, 1.80 MB

english, 2018

39

High-Throughput NIR-Chemometric Method for Meloxicam Assay from Powder Blends for Tableting

Journal:

Scientia Pharmaceutica

Year:

2011

Language:

english

File:

PDF, 310 KB

english, 2011

40

Evaluation of bioactive compounds-loaded chitosan films as a novel and potential diabetic wound dressing material

Colobatiu, Liora, Gavan, Alexandru, Potarniche, Adrian-Valentin, Rus, Vasile, Diaconeasa, Zorita, Mocan, Andrei, Tomuta, Ioan, Mirel, Simona, Mihaiu, Marian

Journal:

Reactive and Functional Polymers

Year:

2019

Language:

english

File:

PDF, 5.46 MB

english, 2019

41

High-throughput NIR-chemometric methods for determination of drug content and pharmaceutical properties of indapamide tablets

Tomuta, Ioan, Rus, Lucia, Iovanov, Rares, Rus, Luca Liviu

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2013

Language:

english

File:

PDF, 1.00 MB

english, 2013

42

Development of antiproliferative long-circulating liposomes co-encapsulating doxorubicin and curcumin, through the use of a quality-by-design approach

Tefas, Lucia Ruxandra, Sylvester, Bianca, Tomuta, Ioan, Sesarman, Alina, Licarete, Emilia, Banciu, Manuela, Porfire, Alina

Journal:

Drug Design Development and Therapy

Year:

2017

Language:

english

File:

PDF, 2.16 MB

english, 2017

43

The Influence of Formulation Factors on the Kinetic Release of Metoprolol Tartrate from Prolong Release Coated Minitablets

Tomuta, Ioan, Leucuta, S. E.

Journal:

Drug Development and Industrial Pharmacy

Year:

2007

Language:

english

File:

PDF, 242 KB

english, 2007

44

Assessment of oral formulation-dependent characteristics of orodispersible tablets using texture profiles and multivariate data analysis

Casian, Tibor, Bogdan, Cătălina, Tarta, Diana, Moldovan, Mirela, Tomuta, Ioan, Iurian, Sonia

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2018

Language:

english

File:

PDF, 1.73 MB

english, 2018

45

Formulation, preparation and in vitro - in vivo evaluation of compression-coated tablets for the colonic-specific release of ketoprofen

Hales, Dana, Dumitrașcu, Dan Lucian, Tomuță, Ioan, Briciu, Corina, Muntean, Dana-Maria, Tefas, Lucia Ruxandra, Iurian, Sonia, Iovanov, Rareș Iuliu, Achim, Marcela, Vlase, Laurian

Journal:

Brazilian Journal of Pharmaceutical Sciences

Year:

2018

File:

PDF, 1.68 MB

2018

46

Formulation Optimization of Freeze-Dried Long-Circulating Liposomes and In-Line Monitoring of the Freeze-Drying Process using an NIR Spectroscopy Tool

Sylvester, Bianca, Porfire, Alina, Van bockstal, Pieter-Jan, Porav, Sebastian, Achim, Marcela, Beer, Thomas DE., Tomuță, Ioan

Journal:

Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 1.50 MB

english, 2017

47

Investigation of a Potential Pharmacokinetic Interaction Between Nebivolol and Fluvoxamine in Healthy Volunteers

Gheldiu, Ana-Maria, Vlase, Laurian, Popa, Adina, Briciu, Corina, Muntean, Dana, Bocsan, Corina, Buzoianu, Anca, Achim, Marcela, Tomuta, Ioan, Todor, Ioana, Neag, Maria

Journal:

Journal of Pharmacy and Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 316 KB

english, 2017

48

Optimization of the sonication process for meloxicam nanocrystals preparation

Iurian, Sonia, Tomuţa, Ioan, Rus, Lucia, Achim, Marcela, Leucuta, Sorin E.

Journal:

Year:

2015

Language:

english

File:

PDF, 773 KB

english, 2015

49

Development and optimization of quercetin-loaded PLGA nanoparticles by experimental design

Tefas, Lucia Ruxandra, Tomuță, Ioan, Achim, Marcela, Vlase, Laurian

Journal:

Medicine and Pharmacy Reports

Year:

2015

Language:

english

File:

PDF, 2.13 MB

english, 2015

50

Simultaneous Quantification of Paracetamol and Caffeine in Powder Blends for Tableting by NIR-Chemometry

Muntean, Dana Maria, Alecu, Cristian, Tomuta, Ioan

Journal:

Journal of Spectroscopy

Year:

2017

Language:

english

File:

PDF, 1.62 MB

english, 2017

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